San Francisco 49ers DE Nick Bosa (non-injury), OT Spencer Burford (knee), DE Yetur Gross-Matos (knee), WR Jauan Jennings (ankle, shoulder), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) did not participate in practice Wednesday, Sept. 17. QB Brock Purdy (shoulder, toe) was limited during practice, while RB Jordan James (finger) fully participated in practice.
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