San Francisco 49ers RB Christian McCaffrey (non-injury), WR Ricky Pearsall (knee), DE Mykel Williams (knee) and OT Trent Williams (non-injury) did not participate in practice Wednesday, Nov. 5. LB Tatum Bethune (thigh), C Jake Brendel (hamstring), DE Bryce Huff (hamstring), QB Brock Purdy (toe) and LB Dee Winters (knee) were limited during practice. OG Ben Bartch (ankle), WR Jauan Jennings (ankle, shoulder), QB Mac Jones (knee) and CB Darrell Luter Jr. (Achilles) fully participated in practice.
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