San Francisco 49ers LB Tatum Bethune (knee), DE Nick Bosa (hip, oblique), WR Jacob Cowing (concussion) and DT Kevin Givens (groin) did not participate in practice Friday, Nov. 22, and have been ruled out for Week 12. CB Charvarius Ward (non-injury) was limited during practice but has been ruled out. OT Trent Williams (ankle) did not practice and is listed as questionable. C Jon Feliciano (knee) was limited during practice and is listed as questionable.
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