San Francisco 49ers C Jake Brendel (hamstring), DE Yetur Gross-Matos (hamstring, knee), DE Bryce Huff (hamstring) WR Ricky Pearsall (knee) did not participate in practice Friday, Oct. 24, and have been ruled out for Week 8. QB Brock Purdy (toe) was limited during practice but has been ruled out. OT Spencer Burford (knee), LB Luke Gifford (hamstring) and CB Deommodore Lenoir (quadriceps) were limited during practice and are listed as questionable. DT Kalia Davis (hand), CB Renardo Green (toe), WR Jauan Jennings (ankle, rib, shoulder), QB Mac Jones (knee, oblique), RB Christian McCaffrey (non-injury), CB Upton Stout (ankle), DT CJ West (thumb) and OT Trent Williams (non-injury) fully participated in practice and are not on the injury report.
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